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How to fix DNA breaks: new insights into the mechanism of non-homologous end joining
Non-homologous end joining (NHEJ) is the major pathway for the repair of ionizing radiation-induced DNA double-strand breaks (DSBs) in human cells and is essential for the generation of mature T and B cells in the adaptive immune system via the process of V(D)J recombination. Here, we review how rec...
Autores principales: | Vogt, Alex, He, Yuan, Lees-Miller, Susan P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657183/ https://www.ncbi.nlm.nih.gov/pubmed/37787023 http://dx.doi.org/10.1042/BST20220741 |
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