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miR-135a-5p overexpression in peripheral blood-derived exosomes mediates vascular injury in type 2 diabetes patients

OBJECTIVE: Diabetes pathology relies on exosomes (Exos). This study investigated how peripheral blood Exo-containing microRNAs (miRNAs) cause vascular injury in type 2 diabetes (T2D). METHODS: We removed DEmiRNA from T2D chip data from the GEO database. We isolated Exo from 15 peripheral blood sampl...

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Detalles Bibliográficos
Autores principales: Xie, Kangling, Li, Cui, Wang, Mingzhu, Fu, Siqian, Cai, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657216/
https://www.ncbi.nlm.nih.gov/pubmed/38027164
http://dx.doi.org/10.3389/fendo.2023.1035029