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Asymmetric CRISPR enabling cascade signal amplification for nucleic acid detection by competitive crRNA
Nucleic acid detection powered by CRISPR technology provides a rapid, sensitive, and deployable approach to molecular diagnostics. While exciting, there remain challenges limiting its practical applications, such as the need for pre-amplification and the lack of quantitative ability. Here, we develo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657364/ https://www.ncbi.nlm.nih.gov/pubmed/37980404 http://dx.doi.org/10.1038/s41467-023-43389-7 |