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The homeodomain transcriptional regulator DVE-1 directs a program for synapse elimination during circuit remodeling

The elimination of synapses during circuit remodeling is critical for brain maturation; however, the molecular mechanisms directing synapse elimination and its timing remain elusive. We show that the transcriptional regulator DVE-1, which shares homology with special AT-rich sequence-binding (SATB)...

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Detalles Bibliográficos
Autores principales: Alexander, Kellianne D., Ramachandran, Shankar, Biswas, Kasturi, Lambert, Christopher M., Russell, Julia, Oliver, Devyn B., Armstrong, William, Rettler, Monika, Liu, Samuel, Doitsidou, Maria, Bénard, Claire, Walker, Amy K., Francis, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657367/
https://www.ncbi.nlm.nih.gov/pubmed/37980357
http://dx.doi.org/10.1038/s41467-023-43281-4