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scReadSim: a single-cell RNA-seq and ATAC-seq read simulator

Benchmarking single-cell RNA-seq (scRNA-seq) and single-cell Assay for Transposase-Accessible Chromatin using sequencing (scATAC-seq) computational tools demands simulators to generate realistic sequencing reads. However, none of the few read simulators aim to mimic real data. To fill this gap, we i...

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Detalles Bibliográficos
Autores principales: Yan, Guanao, Song, Dongyuan, Li, Jingyi Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657386/
https://www.ncbi.nlm.nih.gov/pubmed/37980428
http://dx.doi.org/10.1038/s41467-023-43162-w