Iron derived from NCOA4-mediated ferritinophagy causes cellular senescence via the cGAS-STING pathway

Cellular senescence is a hallmark of aging and has been linked to age-related diseases. Age-related macular degeneration (AMD), the most common aging-related retinal disease, is prospectively associated with retinal pigment epithelial (RPE) senescence. However, the mechanism of RPE cell senescence r...

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Detalles Bibliográficos
Autores principales: Li, Hong-Ying, Wei, Ting-Ting, Zhuang, Miao, Tan, Cheng-Ye, Xie, Tian-Hua, Cai, Jiping, Yao, Yong, Zhu, Lingpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657394/
https://www.ncbi.nlm.nih.gov/pubmed/37980349
http://dx.doi.org/10.1038/s41420-023-01712-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657394/
https://www.ncbi.nlm.nih.gov/pubmed/37980349
http://dx.doi.org/10.1038/s41420-023-01712-7

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