Thrombospondin1 antagonist peptide treatment attenuates obesity-associated chronic inflammation and metabolic disorders in a diet-induced obese mouse model

Thrombospondin1 (TSP1) is a multifunctional matricellular protein. Previously, we demonstrated that TSP1 plays a pivotal role in obesity-related inflammation and insulin resistance (IR) by modulating macrophage accumulation and activation in adipose tissue. Moreover, in our in vitro studies, a CD36-...

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Detalles Bibliográficos
Autores principales: Zhou, Qi, Gwag, Taesik, Wang, Shuxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657402/
https://www.ncbi.nlm.nih.gov/pubmed/37980376
http://dx.doi.org/10.1038/s41598-023-47635-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657402/
https://www.ncbi.nlm.nih.gov/pubmed/37980376
http://dx.doi.org/10.1038/s41598-023-47635-2

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