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Explainable deep learning for tumor dynamic modeling and overall survival prediction using Neural-ODE

While tumor dynamic modeling has been widely applied to support the development of oncology drugs, there remains a need to increase predictivity, enable personalized therapy, and improve decision-making. We propose the use of Tumor Dynamic Neural-ODE (TDNODE) as a pharmacology-informed neural networ...

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Detalles Bibliográficos
Autores principales: Laurie, Mark, Lu, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657412/
https://www.ncbi.nlm.nih.gov/pubmed/37980358
http://dx.doi.org/10.1038/s41540-023-00317-1