Cargando…

GCparagon: evaluating and correcting GC biases in cell-free DNA at the fragment level

Analyses of cell-free DNA (cfDNA) are increasingly being employed for various diagnostic and research applications. Many technologies aim to increase resolution, e.g. for detecting early-stage cancer or minimal residual disease. However, these efforts may be confounded by inherent base composition b...

Descripción completa

Detalles Bibliográficos
Autores principales: Spiegl, Benjamin, Kapidzic, Faruk, Röner, Sebastian, Kircher, Martin, Speicher, Michael R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657415/
https://www.ncbi.nlm.nih.gov/pubmed/38025047
http://dx.doi.org/10.1093/nargab/lqad102