Characterizing the regulatory Fas (CD95) epitope critical for agonist antibody targeting and CAR-T bystander function in ovarian cancer

Receptor clustering is the most critical step to activate extrinsic apoptosis by death receptors belonging to the TNF superfamily. Although clinically unsuccessful, using agonist antibodies, the death receptors-5 remains extensively studied from a cancer therapeutics perspective. However, despite it...

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Detalles Bibliográficos
Autores principales: Mondal, Tanmoy, Gaur, Himanshu, Wamba, Brice E. N., Michalak, Abby Grace, Stout, Camryn, Watson, Matthew R., Aleixo, Sophia L., Singh, Arjun, Condello, Salvatore, Faller, Roland, Leiserowitz, Gary Scott, Bhatnagar, Sanchita, Tushir-Singh, Jogender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657439/
https://www.ncbi.nlm.nih.gov/pubmed/37838774
http://dx.doi.org/10.1038/s41418-023-01229-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657439/
https://www.ncbi.nlm.nih.gov/pubmed/37838774
http://dx.doi.org/10.1038/s41418-023-01229-7

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