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Ferroptosis sensitization in glioma: exploring the regulatory mechanism of SOAT1 and its therapeutic implications

Glioma, the most common primary malignant tumor of the central nervous system, lacks effective targeted therapies. This study investigates the role of SOAT1, a key gene involved in cholesterol esterification, in glioma prognosis and its association with ferroptosis. Although the impact of SOAT1 on g...

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Detalles Bibliográficos
Autores principales: Sun, Shicheng, Qi, Guoliang, Chen, Hao, He, Dong, Ma, Dengzhen, Bie, Yifan, Xu, Linzong, Feng, Bin, Pang, Qi, Guo, Hua, Zhang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657441/
https://www.ncbi.nlm.nih.gov/pubmed/37980334
http://dx.doi.org/10.1038/s41419-023-06282-1