NINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosis

Plasma membrane permeabilization (PMP) is a defining feature of regulated necrosis. It allows the extracellular release of damage-associated molecular patterns (DAMPs) that trigger sterile inflammation. The pore forming molecules MLKL and GSDMs drive PMP in necroptosis and pyroptosis, respectively,...

Descripción completa

Detalles Bibliográficos
Autores principales: Dondelinger, Yves, Priem, Dario, Huyghe, Jon, Delanghe, Tom, Vandenabeele, Peter, Bertrand, Mathieu J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657445/
https://www.ncbi.nlm.nih.gov/pubmed/37980412
http://dx.doi.org/10.1038/s41419-023-06284-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657445/
https://www.ncbi.nlm.nih.gov/pubmed/37980412
http://dx.doi.org/10.1038/s41419-023-06284-z

Ejemplares similares