Cargando…
NINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosis
Plasma membrane permeabilization (PMP) is a defining feature of regulated necrosis. It allows the extracellular release of damage-associated molecular patterns (DAMPs) that trigger sterile inflammation. The pore forming molecules MLKL and GSDMs drive PMP in necroptosis and pyroptosis, respectively,...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657445/ https://www.ncbi.nlm.nih.gov/pubmed/37980412 http://dx.doi.org/10.1038/s41419-023-06284-z |