Cargando…

Increased Heat Pain Tolerance but Hyperalgesia to Tonic Inflammatory Pain in the CRND8 Mouse Model of Alzheimer’s Disease

BACKGROUND: The effects of Alzheimer’s disease (AD) pathology on the experience of pain are poorly understood. OBJECTIVE: To understand the pathophysiological mechanisms underlying pain sensory transmission in the transgenic mouse model of AD, CRND8. METHODS: We explored AD-related pathology in the...

Descripción completa

Detalles Bibliográficos
Autores principales: Merlo, Sara, Costa, Lara, Chiechio, Santina, Busceti, Carla Letizia, Ciranna, Lucia, Santangelo, Rosa, Sortino, Maria Angela, Fornai, Francesco, Nicoletti, Ferdinando, Copani, Agata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657672/
https://www.ncbi.nlm.nih.gov/pubmed/37742639
http://dx.doi.org/10.3233/JAD-230148