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Increased Heat Pain Tolerance but Hyperalgesia to Tonic Inflammatory Pain in the CRND8 Mouse Model of Alzheimer’s Disease

BACKGROUND: The effects of Alzheimer’s disease (AD) pathology on the experience of pain are poorly understood. OBJECTIVE: To understand the pathophysiological mechanisms underlying pain sensory transmission in the transgenic mouse model of AD, CRND8. METHODS: We explored AD-related pathology in the...

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Detalles Bibliográficos
Autores principales:	Merlo, Sara, Costa, Lara, Chiechio, Santina, Busceti, Carla Letizia, Ciranna, Lucia, Santangelo, Rosa, Sortino, Maria Angela, Fornai, Francesco, Nicoletti, Ferdinando, Copani, Agata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657672/ https://www.ncbi.nlm.nih.gov/pubmed/37742639 http://dx.doi.org/10.3233/JAD-230148

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