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Incretin Mimetics Restore the ER-Mitochondrial Axis and Switch Cell Fate Towards Survival in LUHMES Dopaminergic-Like Neurons: Implications for Novel Therapeutic Strategies in Parkinson’s Disease

BACKGROUND: Parkinson’s disease (PD) is a progressive neurodegenerative movement disorder that afflicts more than 10 million people worldwide. Available therapeutic interventions do not stop disease progression. The etiopathogenesis of PD includes unbalanced calcium dynamics and chronic dysfunction...

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Detalles Bibliográficos
Autores principales: Panagaki, Theodora, Randi, Elisa B., Szabo, Csaba, Hölscher, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657688/
https://www.ncbi.nlm.nih.gov/pubmed/37718851
http://dx.doi.org/10.3233/JPD-230030