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Incretin Mimetics Restore the ER-Mitochondrial Axis and Switch Cell Fate Towards Survival in LUHMES Dopaminergic-Like Neurons: Implications for Novel Therapeutic Strategies in Parkinson’s Disease
BACKGROUND: Parkinson’s disease (PD) is a progressive neurodegenerative movement disorder that afflicts more than 10 million people worldwide. Available therapeutic interventions do not stop disease progression. The etiopathogenesis of PD includes unbalanced calcium dynamics and chronic dysfunction...
Autores principales: | Panagaki, Theodora, Randi, Elisa B., Szabo, Csaba, Hölscher, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657688/ https://www.ncbi.nlm.nih.gov/pubmed/37718851 http://dx.doi.org/10.3233/JPD-230030 |
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