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A human 3D immune competent full-thickness skin model mimicking dermal dendritic cell activation

We have integrated dermal dendritic cell surrogates originally generated from the cell line THP-1 as central mediators of the immune reaction in a human full-thickness skin model. Accordingly, sensitizer treatment of THP-1-derived CD14(-), CD11c(+) immature dendritic cells (iDCs) resulted in the pho...

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Detalles Bibliográficos
Autores principales: Hölken, Johanna Maria, Friedrich, Katja, Merkel, Marion, Blasius, Nelli, Engels, Ursula, Buhl, Timo, Mewes, Karsten Rüdiger, Vierkotten, Lars, Teusch, Nicole Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657825/
https://www.ncbi.nlm.nih.gov/pubmed/38022577
http://dx.doi.org/10.3389/fimmu.2023.1276151