Targeting PD-1/PD-L1 inhibits rejection in a heterotopic tracheal allograft model of lung transplantation

Immune checkpoint molecules such as programmed death-1 (PD-1) and programmed death ligand-1 (PD-L1) have revolutionized the field of lung cancer treatment. As part of our study, we examined the role of these proteins in acute rejection in a mouse model of heterotopic tracheal transplantation. Recipi...

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Detalles Bibliográficos
Autores principales: Kaiho, Taisuke, Suzuki, Hidemi, Hata, Atsushi, Matsumoto, Hiroki, Tanaka, Kazuhisa, Sakairi, Yuichi, Motohashi, Shinichiro, Yoshino, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657857/
https://www.ncbi.nlm.nih.gov/pubmed/38026994
http://dx.doi.org/10.3389/fphar.2023.1298085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657857/
https://www.ncbi.nlm.nih.gov/pubmed/38026994
http://dx.doi.org/10.3389/fphar.2023.1298085

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