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Targeting PD-1/PD-L1 inhibits rejection in a heterotopic tracheal allograft model of lung transplantation
Immune checkpoint molecules such as programmed death-1 (PD-1) and programmed death ligand-1 (PD-L1) have revolutionized the field of lung cancer treatment. As part of our study, we examined the role of these proteins in acute rejection in a mouse model of heterotopic tracheal transplantation. Recipi...
Autores principales: | Kaiho, Taisuke, Suzuki, Hidemi, Hata, Atsushi, Matsumoto, Hiroki, Tanaka, Kazuhisa, Sakairi, Yuichi, Motohashi, Shinichiro, Yoshino, Ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657857/ https://www.ncbi.nlm.nih.gov/pubmed/38026994 http://dx.doi.org/10.3389/fphar.2023.1298085 |
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