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A unique role for IL-13 in inducing esophageal eosinophilia through MID-1 and STAT6

INTRODUCTION: Eosinophilic esophagitis (EoE) is associated with allergen-driven inflammation of the esophagus and an upregulated Th2 cytokine signature. Recombinant interleukin (IL)-13 (rIL-13) administration to mice induces some of the hallmark features of EoE, including increased eotaxin expressio...

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Detalles Bibliográficos
Autores principales: Girkin, Jason L. N., Sokulsky, Leon A., Starkey, Malcolm R., Hansbro, Philip M., Foster, Paul S., Collison, Adam M., Mattes, Joerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657859/
https://www.ncbi.nlm.nih.gov/pubmed/38026128
http://dx.doi.org/10.3389/falgy.2023.1248432