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Protective effects of dioscin against Parkinson's disease via regulating bile acid metabolism through remodeling gut microbiome/GLP-1 signaling

It is necessary to explore potent therapeutic agents via regulating gut microbiota and metabolism to combat Parkinson's disease (PD). Dioscin, a bioactive steroidal saponin, shows various activities. However, its effects and mechanisms against PD are limited. In this study, dioscin dramatically...

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Detalles Bibliográficos
Autores principales: Mao, Zhang, Hui, Haochen, Zhao, Xuerong, Xu, Lina, Qi, Yan, Yin, Lianhong, Qu, Liping, Han, Lan, Peng, Jinyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657977/
https://www.ncbi.nlm.nih.gov/pubmed/38024855
http://dx.doi.org/10.1016/j.jpha.2023.06.007