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An efficient evaluation system for factors affecting the genome editing efficiency in mouse

Genome editing technology is widely used in the field of laboratory animal science for the production of genetic disease models and the analysis of gene function. One of the major technical problems in genome editing is the low efficiency of precise knock-in by homologous recombination compared to s...

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Detalles Bibliográficos
Autores principales: Sakai, Yusuke, Okabe, Yuri, Itai, Gen, Shiozawa, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658088/
https://www.ncbi.nlm.nih.gov/pubmed/37407493
http://dx.doi.org/10.1538/expanim.23-0045