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Apolipoprotein E-depletion accelerates arterial fat deposition in the spontaneously hypertensive rat

Hypertension and atherosclerosis are often found in one patient causing serious cardiovascular events. An animal model simultaneously expressing hypertension and atherosclerosis would be useful to study such a complex risk status. We therefore attempted to introduce a null mutation of the apolipopro...

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Detalles Bibliográficos
Autores principales: Matsuo, Hiroyuki, Kawakami, Kohei, Ohara, Hiroki, Kaneko, Takehito, Mashimo, Tomoji, Yamada, Takaya, Nabika, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658095/
https://www.ncbi.nlm.nih.gov/pubmed/37081644
http://dx.doi.org/10.1538/expanim.23-0012