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Mechanosensitive ion channel Piezo1 mediates mechanical ventilation-exacerbated ARDS-associated pulmonary fibrosis

INTRODUCTION: Pulmonary fibrosis is a major cause of the poor prognosis of acute respiratory distress syndrome (ARDS). While mechanical ventilation (MV) is an indispensable life-saving intervention for ARDS, it may cause the remodeling process in lung epithelial cells to become disorganized and exac...

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Detalles Bibliográficos
Autores principales: Fang, Xiang-Zhi, Li, Min, Wang, Ya-Xin, Zhang, Pei, Sun, Miao-Miao, Xu, Jia-Xin, Yang, Yi-Yi, He, Ya-Jun, Yu, Yuan, Li, Rui-Ting, Zhou, Ting, Reng, Le-Hao, Sun, De-Yi, Shu, Hua-Qing, Yuan, Shi-Ying, Xu, Ji-Qian, Shang, You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658225/
https://www.ncbi.nlm.nih.gov/pubmed/36526145
http://dx.doi.org/10.1016/j.jare.2022.12.006