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Obacunone targets macrophage migration inhibitory factor (MIF) to impede osteoclastogenesis and alleviate ovariectomy-induced bone loss

INTRODUCTION: Osteoporosis is the most common bone disorder where the hyperactive osteoclasts represent the leading role during the pathogenesis. Targeting hyperactive osteoclasts is currently the primary therapeutic strategy. However, concerns about the long-term efficacy and side effects of curren...

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Detalles Bibliográficos
Autores principales: He, Jianbo, Zheng, Lin, Li, Xiaojuan, Huang, Furong, Hu, Sitao, Chen, Lei, Jiang, Manya, Lin, Xianfeng, Jiang, Haibo, Zeng, Yifan, Ye, Tianshen, Lin, Dingkun, Liu, Qian, Xu, Jiake, Chen, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658311/
https://www.ncbi.nlm.nih.gov/pubmed/36657717
http://dx.doi.org/10.1016/j.jare.2023.01.003