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Utilizing induced neural stem cell‐based delivery of a cytokine cocktail to enhance chimeric antigen receptor‐modified T‐cell therapy for brain cancer

Chimeric antigen receptor (CAR)‐modified T‐cell therapy has shown enormous clinical promise against blood cancers, yet efficacy against solid tumors remains a challenge. Here, we investigated the potential of a new combination cell therapy, where tumor‐homing induced neural stem cells (iNSCs) are us...

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Detalles Bibliográficos
Autores principales: Woodell, Alex S., Landoni, Elisa, Valdivia, Alain, Buckley, Andrew, Ogunnaike, Edikan A., Dotti, Gianpietro, Hingtgen, Shawn D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658508/
https://www.ncbi.nlm.nih.gov/pubmed/38023712
http://dx.doi.org/10.1002/btm2.10538