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Population pharmacokinetic analysis of enrofloxacin and its active metabolite ciprofloxacin after intravenous injection to cats with reduced kidney function

BACKGROUND: It is unknown if enrofloxacin accumulates in plasma of cats with reduced kidney function. HYPOTHESIS: To determine if enrofloxacin and its active metabolite ciprofloxacin have reduced clearance in azotemic cats. ANIMALS: Thirty‐four cats hospitalized for clinical illness with variable de...

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Detalles Bibliográficos
Autores principales: Foster, Jonathan D., Abouraya, Mahmoud, Papich, Mark G., Muma, Nancy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658592/
https://www.ncbi.nlm.nih.gov/pubmed/37728198
http://dx.doi.org/10.1111/jvim.16866