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Exosomes from M2c macrophages alleviate intervertebral disc degeneration by promoting synthesis of the extracellular matrix via MiR‐124/CILP/TGF‐β

Immuno‐inflammation is highly associated with anabolic and catabolic dysregulation of the extracellular matrix (ECM) in the nucleus pulposus (NP), which dramatically propels intervertebral disc degeneration (IVDD). With the characteristics of tissue remodeling and regeneration, M2c macrophages have...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Xue, Mintao, Han, Yaguang, Li, Yucai, Xiao, Bing, Wang, Weiheng, Yu, Jiangming, Ye, Xiaojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658595/
https://www.ncbi.nlm.nih.gov/pubmed/38023721
http://dx.doi.org/10.1002/btm2.10500