Cargando…
Exosomes from M2c macrophages alleviate intervertebral disc degeneration by promoting synthesis of the extracellular matrix via MiR‐124/CILP/TGF‐β
Immuno‐inflammation is highly associated with anabolic and catabolic dysregulation of the extracellular matrix (ECM) in the nucleus pulposus (NP), which dramatically propels intervertebral disc degeneration (IVDD). With the characteristics of tissue remodeling and regeneration, M2c macrophages have...
Autores principales: | Liu, Yi, Xue, Mintao, Han, Yaguang, Li, Yucai, Xiao, Bing, Wang, Weiheng, Yu, Jiangming, Ye, Xiaojian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658595/ https://www.ncbi.nlm.nih.gov/pubmed/38023721 http://dx.doi.org/10.1002/btm2.10500 |
Ejemplares similares
-
Transplantation of allogenic nucleus pulposus cells attenuates intervertebral disc degeneration by inhibiting apoptosis and increasing migration
por: Wang, Weiheng, et al.
Publicado: (2018) -
Association between CILP and IL-1α polymorphisms and phenotype-dependent intervertebral disc degeneration susceptibility: A meta-analysis
por: Liu, Jiachen, et al.
Publicado: (2022) -
Genipin Cross-Linked Decellularized Nucleus Pulposus Hydrogel-Like Cell Delivery System Induces Differentiation of ADSCs and Retards Intervertebral Disc Degeneration
por: Yu, Lei, et al.
Publicado: (2021) -
MiR-330-5p inhibits intervertebral disk degeneration via targeting CILP
por: Li, Shangzhi, et al.
Publicado: (2021) -
Transplantation of Hypoxic-Preconditioned Bone Mesenchymal Stem Cells Retards Intervertebral Disc Degeneration via Enhancing Implanted Cell Survival and Migration in Rats
por: Wang, Weiheng, et al.
Publicado: (2018)