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Protective effects of pyrroloquinoline quinone in brain folate deficiency

BACKGROUND: Folates (Vitamin B9) are critical for normal neurodevelopment and function, with transport mediated by three major pathways: folate receptor alpha (FRα), proton-coupled folate transporter (PCFT), and reduced folate carrier (RFC). Cerebral folate uptake primarily occurs at the blood-cereb...

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Detalles Bibliográficos
Autores principales: Sangha, Vishal, Aboulhassane, Sara, Qu, Qing Rui, Bendayan, Reina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659058/
https://www.ncbi.nlm.nih.gov/pubmed/37981683
http://dx.doi.org/10.1186/s12987-023-00488-3