Spt5 C-terminal repeat domain phosphorylation and length negatively regulate heterochromatin through distinct mechanisms

Heterochromatin is a condensed chromatin structure that represses transcription of repetitive DNA elements and developmental genes, and is required for genome stability. Paradoxically, transcription of heterochromatic sequences is required for establishment of heterochromatin in diverse eukaryotic s...

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Detalles Bibliográficos
Autores principales: MacKinnon, Sarah, Pagé, Viviane, Chen, Jennifer J., Shariat-Panahi, Ali, Martin, Ryan D., Hébert, Terence E., Tanny, Jason C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659198/
https://www.ncbi.nlm.nih.gov/pubmed/37939109
http://dx.doi.org/10.1371/journal.pgen.1010492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659198/
https://www.ncbi.nlm.nih.gov/pubmed/37939109
http://dx.doi.org/10.1371/journal.pgen.1010492

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