Targeting Angiotensinogen With N-Acetylgalactosamine–Conjugated Small Interfering RNA to Reduce Blood Pressure

Blood pressure management involves antihypertensive therapies blocking the renin-angiotensin system (RAS). Yet, it might be inadequate due to poor patient adherence or the so-called RAS escape phenomenon, elicited by the compensatory renin elevation upon RAS blockade. Recently, evidence points towar...

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Detalles Bibliográficos
Autores principales: Ye, Dien, Cruz-López, Edwyn O., Tu, Ho-Chou, Zlatev, Ivan, Danser, A.H. Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
ATVB in Focus: Emerging Genomic-Based Therapies for Cardiovascular Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659251/
https://www.ncbi.nlm.nih.gov/pubmed/37855126
http://dx.doi.org/10.1161/ATVBAHA.123.319897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659251/
https://www.ncbi.nlm.nih.gov/pubmed/37855126
http://dx.doi.org/10.1161/ATVBAHA.123.319897

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