Dengue virus exploits the host tRNA epitranscriptome to promote viral replication

The 40–50 RNA modifications of the epitranscriptome regulate posttranscriptional gene expression. Here we show that flaviviruses hijack the host tRNA epitranscriptome to promote expression of pro-viral proteins, with tRNA-modifying ALKBH1 acting as a host restriction factor in dengue virus infection...

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Detalles Bibliográficos
Autores principales: Chan, Cheryl, Kwan Sze, Newman Siu, Suzuki, Yuka, Ohira, Takayuki, Suzuki, Tsutomu, Begley, Thomas J., Dedon, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659268/
https://www.ncbi.nlm.nih.gov/pubmed/37986976
http://dx.doi.org/10.1101/2023.11.05.565734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659268/
https://www.ncbi.nlm.nih.gov/pubmed/37986976
http://dx.doi.org/10.1101/2023.11.05.565734

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