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In Vivo Biorthogonal Antibody Click for Dual Targeting and Augmented Efficacy in Cancer Treatment

Antibody-drug conjugates (ADCs) have emerged as promising therapeutics for cancer treatment; however, their effectiveness has been limited by single antigen targeting, potentially leading to resistance mechanisms triggered by tumor compensatory pathways or reduced expression of the target protein. H...

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Detalles Bibliográficos
Autores principales: Panikar, Sandeep Surendra, Berry, Na-Keysha, Shmuel, Shayla, Keltee, Nai, Pereira, Patrícia M.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659283/
https://www.ncbi.nlm.nih.gov/pubmed/37986985
http://dx.doi.org/10.1101/2023.09.05.556426