Determination of Metabolic Fluxes by Deep Learning of Isotope Labeling Patterns

Fluxomics offers a direct readout of metabolic state but relies on indirect measurement. Stable isotope tracers imprint flux-dependent isotope labeling patterns on metabolites we measure; however, the relationship between labeling patterns and fluxes remains elusive. Here we innovate a two-stage mac...

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Detalles Bibliográficos
Autores principales: Law, Richard C., O’Keeffe, Samantha, Nurwono, Glenn, Ki, Rachel, Lakhani, Aliya, Lai, Pin-Kuang, Park, Junyoung O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659294/
https://www.ncbi.nlm.nih.gov/pubmed/37986781
http://dx.doi.org/10.1101/2023.11.06.565907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659294/
https://www.ncbi.nlm.nih.gov/pubmed/37986781
http://dx.doi.org/10.1101/2023.11.06.565907

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