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Determination of Metabolic Fluxes by Deep Learning of Isotope Labeling Patterns
Fluxomics offers a direct readout of metabolic state but relies on indirect measurement. Stable isotope tracers imprint flux-dependent isotope labeling patterns on metabolites we measure; however, the relationship between labeling patterns and fluxes remains elusive. Here we innovate a two-stage mac...
Autores principales: | Law, Richard C., O’Keeffe, Samantha, Nurwono, Glenn, Ki, Rachel, Lakhani, Aliya, Lai, Pin-Kuang, Park, Junyoung O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659294/ https://www.ncbi.nlm.nih.gov/pubmed/37986781 http://dx.doi.org/10.1101/2023.11.06.565907 |
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