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Rho/ROCK activity tunes cell compartment segregation and differentiation in nephron-forming niches

Controlling the time and place of nephron formation in vitro would improve nephron density and connectivity in next-generation kidney replacement tissues. Recent developments in kidney organoid technology have paved the way to achieving self-sustaining nephrogenic niches in vitro. The physical and g...

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Detalles Bibliográficos
Autores principales: Viola, John M., Liu, Jiageng, Huang, Aria, Grindel, Samuel H., Prahl, Louis S., Hughes, Alex J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659296/
https://www.ncbi.nlm.nih.gov/pubmed/37986773
http://dx.doi.org/10.1101/2023.11.08.566308