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Rho/ROCK activity tunes cell compartment segregation and differentiation in nephron-forming niches
Controlling the time and place of nephron formation in vitro would improve nephron density and connectivity in next-generation kidney replacement tissues. Recent developments in kidney organoid technology have paved the way to achieving self-sustaining nephrogenic niches in vitro. The physical and g...
Autores principales: | Viola, John M., Liu, Jiageng, Huang, Aria, Grindel, Samuel H., Prahl, Louis S., Hughes, Alex J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659296/ https://www.ncbi.nlm.nih.gov/pubmed/37986773 http://dx.doi.org/10.1101/2023.11.08.566308 |
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