Cargando…

Altered hippocampal activation in seizure-prone CACNA2D2 knockout mice

The voltage-gated calcium channel subunit α2δ-2 controls calcium-dependent signaling in neurons, and loss of this subunit causes epilepsy in both mice and humans. To determine whether mice without α2δ-2 demonstrate hippocampal activation or histopathological changes associated with seizure activity,...

Descripción completa

Detalles Bibliográficos
Autores principales: Danis, Alyssa, Gallagher, Ashlynn A., Anderson, Ashley N., Isakharov, Arielle, Beeson, Kathleen A., Schnell, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659305/
https://www.ncbi.nlm.nih.gov/pubmed/37986872
http://dx.doi.org/10.1101/2023.11.08.565511