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Dynamic RNA Polymerase II Recruitment Drives Differentiation of the Intestine under the direction of HNF4

Terminal differentiation requires a massive restructuring of the transcriptome. During intestinal differentiation, the expression patterns of nearly 4000 genes are altered as cells transition from progenitor cells in crypts to differentiated cells in villi. We identified dynamic recruitment of RNA P...

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Detalles Bibliográficos
Autores principales: Vemuri, Kiranmayi, Kumar, Sneha, Chen, Lei, Verzi, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659318/
https://www.ncbi.nlm.nih.gov/pubmed/37986803
http://dx.doi.org/10.1101/2023.11.08.566322