Cargando…

Transcriptomic changes during the replicative senescence of human articular chondrocytes

Osteoarthritis (OA) is a degenerative joint disease and a leading cause of disability worldwide. Aging is a major risk factor for OA, but the specific mechanisms underlying this connection remain unclear. Although chondrocytes rarely divide in adult articular cartilage, they undergo replicative sene...

Descripción completa

Detalles Bibliográficos
Autores principales: Atasoy-Zeybek, Aysegul, Hawse, Gresin P., Nagelli, Christopher V., Lopez De Padilla, Consuelo, Abdel, Matthew P., Evans, Christopher H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659330/
https://www.ncbi.nlm.nih.gov/pubmed/37986862
http://dx.doi.org/10.1101/2023.11.07.565835