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Asymmetrical Bi-antennary Glycans Prepared by a Stop-and-Go Strategy Reveal Receptor Binding Evolution of Human Influenza A Viruses

Glycan binding properties of respiratory viruses have been difficult to probe due to a lack of biological relevant glycans for binding studies. Here, a stop-and-go chemoenzymatic methodology is presented that gave access to a panel of 32 asymmetrical bi-antennary N-glycans having various numbers of...

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Detalles Bibliográficos
Autores principales: Ma, Shengzhou, Liu, Lin, Eggink, Dirk, Herfst, Sander, Fouchier, Ron A.M., de Vries, Robert P., Boons, Geert-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659364/
https://www.ncbi.nlm.nih.gov/pubmed/37986780
http://dx.doi.org/10.1101/2023.11.08.566285