Cargando…

The Na(+) leak channel NALCN controls spontaneous activity and mediates synaptic modulation by α2-adrenergic receptors in auditory neurons

Cartwheel interneurons of the dorsal cochlear nucleus (DCN) potently suppress multisensory signals that converge with primary auditory afferent input, and thus regulate auditory processing. Noradrenergic fibers from locus coeruleus project to the DCN, and α2-adrenergic receptors inhibit spontaneous...

Descripción completa

Detalles Bibliográficos
Autores principales: Ngodup, Tenzin, Irie, Tomohiko, Elkins, Sean, Trussell, Laurence O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659375/
https://www.ncbi.nlm.nih.gov/pubmed/37987013
http://dx.doi.org/10.1101/2023.06.23.546323