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Connecting Chromatin Structures to Gene Regulation Using Dynamic Polymer Simulations

The transfer of regulatory information between distal loci on chromatin is thought to involve physical proximity, but key biophysical features of these contacts remain unclear. For instance, it is unknown how close and for how long two loci need to be in order to productively interact. The main chal...

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Detalles Bibliográficos
Autores principales: Fu, Yi, Clark, Finnegan, Nomikou, Sofia, Tsirigos, Aristotelis, Lionnet, Timothee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659377/
https://www.ncbi.nlm.nih.gov/pubmed/37986912
http://dx.doi.org/10.1101/2023.11.07.566032