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Connecting Chromatin Structures to Gene Regulation Using Dynamic Polymer Simulations
The transfer of regulatory information between distal loci on chromatin is thought to involve physical proximity, but key biophysical features of these contacts remain unclear. For instance, it is unknown how close and for how long two loci need to be in order to productively interact. The main chal...
Autores principales: | Fu, Yi, Clark, Finnegan, Nomikou, Sofia, Tsirigos, Aristotelis, Lionnet, Timothee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659377/ https://www.ncbi.nlm.nih.gov/pubmed/37986912 http://dx.doi.org/10.1101/2023.11.07.566032 |
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