Identification of NanoLuciferase Substrates Transported by Human ABCB1 and ABCG2 and their Zebrafish Homologs at the Blood-Brain Barrier

ATP-binding cassette (ABC) transporters expressed at the blood-brain barrier (BBB) impede delivery of therapeutic agents to the brain, including agents to treat neurodegenerative diseases and primary and metastatic brain cancers. Two transporters, P-glycoprotein (P-gp, ABCB1) and ABCG2, are highly e...

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Detalles Bibliográficos
Autores principales: Inglut, Collin T., Quinlan, John A., Robey, Robert W., Thomas, Joanna R., Walker, Joel R., Zhou, Wenhui, Huang, Huang-Chiao, Gottesman, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659404/
https://www.ncbi.nlm.nih.gov/pubmed/37986908
http://dx.doi.org/10.1101/2023.10.20.563277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659404/
https://www.ncbi.nlm.nih.gov/pubmed/37986908
http://dx.doi.org/10.1101/2023.10.20.563277

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