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Modeling the effect of spatial structure on solid tumor evolution and ctDNA composition

Circulating tumor DNA (ctDNA) monitoring, while sufficiently advanced to reflect tumor evolution in real time and inform on cancer diagnosis, treatment, and prognosis, mainly relies on DNA that originates from cell death via apoptosis or necrosis. In solid tumors, chemotherapy and immune infiltratio...

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Detalles Bibliográficos
Autores principales: Rachman, Thomas, Bartlett, David, Laframboise, William, Wagner, Patrick, Schwartz, Russell, Carja, Oana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659436/
https://www.ncbi.nlm.nih.gov/pubmed/37986965
http://dx.doi.org/10.1101/2023.11.10.566658