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Molecular Basis of Human Trace Amine-Associated Receptor 1 Activation

The human trace amine-associated receptor 1 (hTAAR1, hTA1) is a key regulator of monoaminergic neurotransmission and the actions of psychostimulants. Despite preclinical research demonstrating its tractability as a drug target, its molecular mechanisms of activation remain unclear. Moreover, poorly...

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Detalles Bibliográficos
Autores principales: Zilberg, Gregory, Parpounas, Alexandra K., Warren, Audrey L., Yang, Shifan, Wacker, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659437/
https://www.ncbi.nlm.nih.gov/pubmed/37986760
http://dx.doi.org/10.1101/2023.09.06.556555