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Secreted protein profiling of human aortic smooth muscle cells identifies vascular disease associations

BACKGROUND: Smooth muscle cells (SMCs), which make up the medial layer of arteries, are key cell types involved in cardiovascular diseases (CVD), the leading cause of mortality and morbidity worldwide. In response to microenvironment alterations, SMCs dedifferentiate from a “contractile” to a “synth...

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Detalles Bibliográficos
Autores principales: Aherrahrou, Rédouane, Baig, Ferheen, Theofilatos, Konstantinos, Lue, Dillon, Beele, Alicia, Örd, Tiit, Kaikkonen, Minna U, Aherrahrou, Zouhair, Cheng, Qi, Ghosh, Saikat, Karnewar, Santosh, Karnewar, Vaishnavi, Finn, Aloke, Owens, Gary K., Joner, Michael, Mayr, Manuel, Civelek, Mete
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659471/
https://www.ncbi.nlm.nih.gov/pubmed/37986932
http://dx.doi.org/10.1101/2023.11.10.23298351